Compare prices and buy peptides in the Nootropic & Neurological category from every research peptide vendor, supplier and source we index. Updated daily.
Peptides targeting cognition, mood, and neuroprotection (Semax, Selank, Cerebrolysin) and other CNS-active research compounds.
Most of what vendors sell in this category traces to two Soviet and Russian research programs. The Semax and Selank family came out of the Institute of Molecular Genetics of the Russian Academy of Sciences, and both are built the same way: a short biologically active fragment with the tripeptide Pro-Gly-Pro attached to slow enzymatic degradation.
Semax attaches that tripeptide to a fragment of adrenocorticotropic hormone (ACTH). Selank applies the same construction to tuftsin, a tetrapeptide fragment of immunoglobulin G, and is studied as an anxiolytic. Vendors also sell N-acetylated and amidated variants of both, which they describe as more stable, indexed here as N-Acetyl Semax and N-Acetyl Selank, and they sell the two parent peptides together as a Semax plus Selank blend.
Two other post-Soviet compounds sit alongside them without being peptides at all. Phenibut is beta-phenyl-gamma-aminobutyric acid, a GABA-B receptor agonist introduced into Soviet clinical practice in the 1960s as a tranquilizer, and case reports describe dependence and withdrawal after sustained use. Emoxypine Succinate, marketed as Mexidol, is a 3-hydroxypyridine compound used in Russia for ischemic stroke and other cerebrovascular disorders.
The rest of the category is grouped by target rather than origin.
DSIP, delta sleep-inducing peptide, is named for the slow-wave sleep activity it induced in rabbits, and no receptor for it has been identified.
PE-22-28 works at the ion-channel level. It is a shortened analog of spadin, a peptide derived from the sortilin propeptide, and blocks the TREK-1 potassium channel, a target studied in rodent models of depression.
P-21 is a peptidomimetic derived from ciliary neurotrophic factor and carrying an adamantane group, reported to raise BDNF expression and hippocampal neurogenesis in rodent models.
VIP, vasoactive intestinal peptide, is a neuropeptide of the secretin and glucagon family that signals through the VPAC1 and VPAC2 receptors, with roles in vasodilation, immune regulation and circadian timing.
Nothing in this category is FDA-approved. Three members were caught up in the 2026 compounding changes, and they did not all end the same way.
On April 15, 2026 the FDA announced the removal of twelve substances from Category 2 under section 503A, its list of bulk drug substances that may present significant safety risks, effective seven days later, and Semax, DSIP (listed as emideltide) and Dihexa were three of them. The Pharmacy Compounding Advisory Committee has since recommended adding Semax to the 503A bulks list and declined to recommend DSIP, and Dihexa is due before the committee at a later meeting.
Those votes are advisory. FDA's own reviewers had proposed adding neither Semax nor DSIP, and the bulks list changes only through notice-and-comment rulemaking. In October 2026 HHS issued a policy under which it does not intend to take enforcement action against pharmacies compounding Semax under set conditions until a final rule settles its listing, and our post on the HHS policy covers its terms.
Cerebrolysin is regulated as a finished prescription drug outside the United States. It is a porcine-brain hydrolysate of peptides and free amino acids, made by the Austrian company EVER Pharma and used mainly in stroke and traumatic brain injury, and it is not approved in the United States.
Noopept, also called omberacetam, is a capped dipeptide ester designed at Moscow's Zakusov Institute of Pharmacology as a dipeptide analog of the nootropic piracetam.
Dihexa is an angiotensin IV analog marketed on the claim that it potentiates hepatocyte growth factor at the c-Met receptor, and the primary evidence for that mechanism has been retracted.
Adamax is a vendor name for a compound that vendor sources describe as an adamantane-modified Semax derivative, which is why it is catalogued alongside the ACTH-derived nootropics. As of October 2026 no peer-reviewed paper or public chemical registry gives its structure. Vendors sell two forms distinguished by molecular weight, the 984 form and Adamax 1032, indexed as separate rows.
DNSP-11, an 11-amino-acid fragment of the pro-region of glial cell line-derived neurotrophic factor, and FGL, a mimic of the neural cell adhesion molecule's second fibronectin-type-III domain, are both indexed here.
The committee voted on both on July 24, 2026. It recommended adding Semax to the Section 503A bulk drug substances list by 8 votes to 5, and voted 6 to 7, with one abstention, against DSIP, which FDA documents call emideltide. FDA had proposed adding neither. For DSIP, FDA's briefing found too little evidence of safety and effectiveness in the uses it reviewed (opioid withdrawal, chronic insomnia and narcolepsy) and noted that approved treatments exist for them. Members who voted against it cited weak evidence of efficacy and those approved alternatives. The votes are advisory, and the FDA changes the bulks list only through notice-and-comment rulemaking.
Plain Semax is ACTH(4-7) extended with the tripeptide Pro-Gly-Pro, which slows enzymatic breakdown. N-Acetyl Semax adds an acetyl group at the N-terminus, and the amidate form adds an amide at the C-terminus. The labels N-Acetyl Semax Amidate, NA Semax Amidate and NA-Semax all refer to the modified peptide rather than to plain Semax. Vendors describe the modifications as improving stability. PeptideScouter indexes plain Semax and the N-acetyl form as separate rows because they are different molecules at different prices, so a listing labelled only Semax should not be price-compared against one labelled NA Semax. The same applies to Selank and N-Acetyl Selank.
Chemically, yes. Aviptadil is the international nonproprietary name for synthetic vasoactive intestinal peptide, identical to VIP across all 28 residues including the amidated C-terminus, and the two share CAS 40077-57-4. The difference is context rather than chemistry: aviptadil is the name used in drug development, which has included an erectile dysfunction injection combined with phentolamine and an intravenous treatment for COVID-19 respiratory failure. Neither is FDA-approved. PeptideScouter indexes them as separate rows because vendors price and label them separately.
Partly. In April 2025 the Journal of Pharmacology and Experimental Therapeutics retracted the 2014 paper that proposed dihexa's mechanism, amplification of hepatocyte growth factor signaling at the c-Met receptor, along with earlier papers on related analogs from the same group. The retraction notice cites a Washington State University investigation that found falsified or fabricated data. The 2013 paper that introduced dihexa and reported its activity in rats carries an expression of concern but had not been retracted as of October 2026. No clinical trial has given dihexa itself.
45 vendors tracked by PeptideScouter sell Nootropic & Neurological peptides, across 422 listings covering 21 compounds. The widest Nootropic & Neurological catalogs belong to Disguised Alpha (14 peptides), Flawless Compounds (13 peptides), Glow Aminos (13 peptides). Prices are normalized to USD per milligram and refreshed daily.
Nootropic & Neurological peptides indexed on PeptideScouter have a median price of $4.68/mg, ranging from $0.78/mg to $21.60/mg across the 21 peptides in the category. Pricing is normalized across vendors and refreshed daily.
Cerebrolysin carries the lowest median price in the Nootropic & Neurological category at $0.78/mg across 10 listings. Its cheapest in-stock listing is $0.33/mg at Disguised Alpha. Per-milligram price varies widely between compounds in a category, so the cheapest per mg is not necessarily the cheapest vial or the right compound for a given experiment.
The most widely sold Nootropic & Neurological peptides on PeptideScouter (by vendor count) are: Selank, Semax, DSIP, VIP, Semax + Selank Blend. Each peptide page shows current pricing across every tracked vendor, normalized to USD per milligram.
