A small synthetic peptidomimetic (CAS 1246751-68-7) derived from residues 148-151 of ciliary neurotrophic factor (CNTF) and modified with an adamantane moiety for blood-brain-barrier permeability. A neurogenic compound that elevates BDNF expression and promotes hippocampal adult neurogenesis in rodent models of Alzheimer's disease, fragile X, and traumatic brain injury. Developed at the NIH Laboratory of Neuroscience; no clinical trials initiated. Not FDA-approved.
For research purposes only. Not medical advice.
Ruo Bio currently lists P-21 at $7.60/mg, the lowest indexed price across 2 tracked research peptide vendors.
P-21 ranges from $7.60/mg to $9.92/mg across 3 listings from 2 research peptide vendors, normalized to USD per milligram and refreshed daily.
2 research peptide vendors currently list P-21 on PeptideScouter. We track 3 active listings across size and kit variants.
P-21's CAS Registry Number is 1246751-68-7.