Compare prices and buy peptides in the Sexual Health category from every research peptide vendor, supplier and source we index. Updated daily.
Peptides and small molecules studied for sexual function, including melanocortin-receptor agonists (PT-141 / bremelanotide), premature-ejaculation SSRIs (dapoxetine), and related compounds acting on libido, arousal, or ejaculatory latency.
Sexual-function research compounds reach the same endpoint from opposite directions. One group acts on melanocortin receptors in the nervous system. A second acts far upstream, on the hypothalamic signal that starts the reproductive endocrine cascade. A third entry is neither, and is not a peptide.
In animal studies, MC4 receptor activation modulates erectile function and sexual behavior, through receptors expressed in the hypothalamus, the spinal cord and the nerves of the penis. That is the pathway proposed for both peptides in this branch (the Vyleesi label calls bremelanotide's mechanism in hypoactive sexual desire disorder unknown), and what separates them is approval status rather than selectivity.
Melanotan II is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone that agonizes MC1, MC3, MC4 and MC5 without discrimination. The MC4 activity is thought to underlie the sexual-function effects, and the MC1 activity produces the pigmentation the compound is better known for.
PT-141, bremelanotide, is the version of that scaffold that reached approval, and it differs from Melanotan II by a single change at the C-terminus. It is widely described as a selective redesign of Melanotan II, but its own label calls it nonselective and ranks the pigmentation receptor, MC1R, first in potency.
Kisspeptin-10 reaches sexual function from a completely different level of the system. It is the active 10-amino-acid C-terminal fragment of the KISS1 gene product and a high-potency agonist at the KISS1R receptor, also called GPR54, on hypothalamic GnRH neurons. That places it one step upstream of GnRH itself and two steps upstream of luteinizing hormone.
Its research literature is in reproductive endocrinology, which is why its primary catalog entry sits under Hormonal. It appears here because of brain-imaging work on sexual arousal, which used the longer kisspeptin-54 isoform.
Dapoxetine is a short-acting selective serotonin reuptake inhibitor, and its effect on ejaculatory latency is presumed to come from inhibiting serotonin reuptake. It is a small molecule, catalogued here by mechanism.
One compound in this category holds a current FDA approval, and the approval is narrow. PT-141 is approved as Vyleesi for premenopausal women with acquired, generalized hypoactive sexual desire disorder, and the approval does not extend to men or to postmenopausal women. Flibanserin, a non-peptide tablet sold as Addyi, is also FDA-approved for the condition, and since December 2025 its label covers women under 65 regardless of menopausal status.
Dapoxetine is approved as Priligy for premature ejaculation in several European countries and has no FDA approval.
Melanotan II has no FDA approval. Its nomination for the Section 503A bulk drug substances list was withdrawn and FDA moved it out of Category 2, which is not an authorization to compound it. Kisspeptin-10 is investigational, holds no FDA approval and still sits in Category 2.
Melanotan II sits primarily under Skin and Cosmetic. Kisspeptin-10 sits primarily under Hormonal, where its reproductive-endocrine role belongs. Both appear here because their mechanisms genuinely reach sexual function, and PeptideScouter keeps one page per compound, so a cross-listed peptide shows the same prices and the same vendor set from either category.
PT-141, also called bremelanotide, comes from the Melanotan II scaffold, and the chemical difference between them is a single change: Melanotan II carries a C-terminal amide, PT-141 carries a carboxylic acid in its place. Both are cyclic seven-amino-acid peptides and both agonize melanocortin receptors non-selectively. PT-141 is widely described as a selective redesign, but the FDA-approved label for Vyleesi gives its order of potency as MC1R, MC4R, MC3R, MC5R, MC2R, with MC1R, the pigmentation receptor, first, and lists focal hyperpigmentation among its adverse reactions. The difference that matters is regulatory rather than pharmacological: PT-141 is FDA-approved for a specific indication, and Melanotan II has no FDA approval.
PT-141 is approved by the FDA, under the brand name Vyleesi, for premenopausal women with acquired, generalized hypoactive sexual desire disorder. That is the entire scope of the approval. The approval does not cover men, postmenopausal women, or general use for arousal or performance. Research-grade PT-141 powder sold by the vendors indexed here is not the licensed Vyleesi product and is labeled for laboratory use only.
Because one molecule drives both effects through different receptors. Melanotan II agonizes MC1, MC3, MC4 and MC5 without selectivity. MC1 activation on melanocytes stimulates melanin synthesis, which is the pigmentation use that makes it a Skin and Cosmetic product. MC4 activation is thought to underlie the pro-erectile and libido effects that place it here. PeptideScouter keeps one page per compound rather than duplicating the row, so Melanotan II shows the same vendors and the same prices whichever category you reach it from.
No. Dapoxetine has no FDA approval. Outside the United States it is approved as Priligy for premature ejaculation in several European countries.
45 vendors tracked by PeptideScouter sell Sexual Health peptides, across 179 listings covering 4 compounds. The widest Sexual Health catalogs belong to Disguised Alpha (4 peptides), Peptide Titans (4 peptides), Alpha Peptides (3 peptides). Prices are normalized to USD per milligram and refreshed daily.
Sexual Health peptides indexed on PeptideScouter have a median price of $4.00/mg, ranging from $3.30/mg to $5.15/mg across the 4 peptides in the category. Pricing is normalized across vendors and refreshed daily.
Melanotan II carries the lowest median price in the Sexual Health category at $3.30/mg across 62 listings. Its cheapest in-stock listing is $1.66/mg at Studz Peptides. Per-milligram price varies widely between compounds in a category, so the cheapest per mg is not necessarily the cheapest vial or the right compound for a given experiment.
The most widely sold Sexual Health peptides on PeptideScouter (by vendor count) are: Melanotan II, PT-141, Kisspeptin-10, PT-141 + Oxytocin Blend. Each peptide page shows current pricing across every tracked vendor, normalized to USD per milligram.
