Tesofensine

Tesofensine is a piperidine derivative that acts as a presynaptic triple monoamine reuptake inhibitor (serotonin, noradrenaline, dopamine). Originally developed by NeuroSearch for Parkinson's and Alzheimer's research; repurposed for obesity research after trials showed substantial appetite suppression and weight loss. Not a peptide in the strict sense — included here because the research-chemical market carries it alongside peptide catalogs.