A 26-amino-acid single-chain analog of the B-chain of human relaxin-2 (CAS 1818415-56-3) engineered to retain full RXFP1 receptor binding while exhibiting biased signaling toward pERK over the canonical cAMP pathway. Reproduces relaxin-2's antifibrotic and vasodilatory effects in preclinical cardiac, renal, and lung fibrosis models without its tumorigenic cAMP-driven activity. Not FDA-approved.
For research purposes only. Not medical advice.
Ruo Bio currently lists B7-33 at $6.00/mg (currently out of stock), the lowest indexed price across 1 tracked research peptide vendor.
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B7-33's CAS Registry Number is 1818415-56-3.